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PTPa Antibody (S180) Blocking Peptide

PTPa Antibody (S180) Blocking Peptide

Item no.	ABC-BP8412d
Manufacturer	Abcepta
Amount	500 ug
Category	Neuroscience Protein Aggregation, Clearance & Misfolding Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Deloukas, P., et al., Nature 414(6866):865-871 (2001).Kaplan, R., et al., Proc. Natl. Acad. Sci. U.S.A. 87(18):7000-7004 (1990).Krueger, N.X., et al., EMBO J. 9(10):3241-3252 (1990).Sap, J., et al., Proc. Natl. Acad. Sci. U.S.A. 87(16):6112-6116 (1990).Jirik, F.R., et al., FEBS Lett. 273 (1-2), 239-242 (1990).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Receptor-type tyrosine-protein phosphatase alpha,Protein-tyrosine phosphatase alpha,R-PTP-alpha,PTPRA,PTPA,PTPRL2
Similar products	PTPA, PTPRA, PTPRL2, Receptor-type tyrosine-protein phosphatase alpha, R-PTP-alpha, Protein-tyrosine phosphatase alpha
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP8412d was selected from the S180 region of human PTPa. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	PTPa is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation.
Gene Name	PTPRA
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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