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PTP kappa Antibody (N-term) Blocking peptide

PTP kappa Antibody (N-term) Blocking peptide

Manufacturer	Abcepta
Category	Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Amount	500 ug
Item no.	ABC-BP8417a
eClass 6.1	34160400
eClass 9.0	32160409
Available
Primary Accession	Q15262
Bio Background	PTPkappa, a member of the receptor class 2B subfamily of protein-tyrosine phophatases, is involved in regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. It forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTP-kappa. This Type I membrane protein, localized at adherens junctions, is found at high levels in lung, brain and colon; less in liver, pancreas, stomach, kidney, placenta and mammary carcinoma. It contains 4 fibronectin type III domains, 1 immunoglobulin-like C2-type domain, 1 MAM domain, and 2 protein-tyrosine phosphatase domains.
Bio References	Yang, Y., et al., Gene 186(1):77-82 (1997).Fuchs, M., et al., J. Biol. Chem. 271(28):16712-16719 (1996).
Gene ID	5796
Gene Name	PTPRK
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP8417a was selected from the N-term region of human PTPkappa . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP8417a-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 6/6/2024