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PPP1A (PPP1CA) Antibody (N-term) Blocking peptide

PPP1A (PPP1CA) Antibody (N-term) Blocking peptide

Item no.	ABC-BP8472a
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Cell Biology Cell Status Senescence Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Okada, T., et al., Int. J. Oncol. 25(5):1383-1388 (2004).Nazarov, I.B., et al., Radiat. Res. 160(3):309-317 (2003).Ammosova, T., et al., J. Biol. Chem. 278(34):32189-32194 (2003).Danial, N.N., et al., Nature 424(6951):952-956 (2003).Wang, H., et al., J. Biol. Chem. 277(51):49605-49612 (2002).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit,PP-1A,PPP1CA,PPP1A
Similar products	PP-1A, PPP1CA, PPP1A, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP8472a was selected from the N-term region of human PPP1CA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	PPP1CA is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory.
Gene Name	PPP1CA
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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