MOBKL1B, Recombinant, Human, aa1-216, His-Tag (MOB Kinase Activator 1A, Mob1 alpha, Mob1A, Mob1 Homolog 1B, Mps One Binder Kinase Activator-like 1B, MOB1A, C2orf6, MOB4B, MOBK1B, FLJ10788, FLJ11595)

Blue Ice

27, 2

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.2M sodium chloride, 5mM DTT, 30% glycerol.

MOBKL1B, also known as MOB1B, belongs to the MOB1/phocein family. It stimulates the kinase activity of STK38 and STK38L. MOBKL1B binds to and regulate downstream targets such as the NDR-family protein kinases and LATS1 kinase. Therefore, MOBKL1B participates in cell cycle checkpoint control and tumor inhibition.

Source:
Recombinant protein corresponding to aa1-216 of human MOBKL1B, fused to His-tag at N-terminal, expressed in E. coli.

Molecular Weight:
~27.2kD

AA Sequence:
MGSSHHHHHH SSGLVPRGSH MSFLFSSRSS KTFKPKKNIP EGSHQYELLK HAEATLGSGN LRQAVMLPEG EDLNEWIAVN TVDFFNQINM LYGTITEFCT EASCPVMSAG PRYEYHWADG TNIKKPIKCS APKYIDYLMT WVQDQLDDET LFPSKIGVPF PKNFMSVAKT ILKRLFRVYA HIYHQHFDSV MQLQEEAHLN TSFKHFIFFV QEFNLIDRRE LAPLQELIEK LGSKDR

Applications:
Suitable for use in SDS-PAGE. Other applications not tested.

Recommended Dilutions:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.