NTAL, Recombinant, Human, aa27-243, His-Tag

Blue Ice

26, 2

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol.

NTAL (non-T cell activation linker), as known as LAT2, is transmembrane adaptor protein (TRAP) associated with glycolipid-enriched membrane fractions (GEM or lipid rafts). This protein is primarily expressed in spleen and hematopoietic cells, such as B cells, mast cells, NK cells, and monocytes, but not resting T cells. Defects in NTAL may be a cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS).

Source:
Recombinant corresponding to aa27-243 of human NTAL 6x his tagged, expressed in E.coli.

AA Sequences:
MGSSHHHHHH SSGLVPRGSH MRCSRPGAKR SEKIYQQRSL REDQQSFTGS RTYSLVGQAW PGPLADMAPT RKDKLLQFYP SLEDPASSRY QNFSKGSRHG SEEAYIDPIA MEYYNWGRFS KPPEDDDANS YENVLICKQK TTETGAQQEG IGGLCRGDLS LSLALKTGPT SGLCPSASPE
EDEESEDYQN SASIHQWRES RKVMGQLQRE ASPGPVGSPD EEDGEPDYVN GEVAATEA

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

NTAL, aa27-243, Recombinant, Human (LAT2, Linker for Activation of T Cells Family, Member 2, LAB, Linker for Activation of B Cells, Membrane-associated Adapter Molecule, Non-T-cell Activation Linker, WBS15, WBSCR15, WBSCR5, Williams-Beuren Syndrome C