RNA Binding Motif Protein 8A,Recombinant,Human,aa1-174,His-Tag (RNA-binding Motif Protein 8A,RBM8a,RNA Binding Protein 8A,Binder of OVCA1 1,Binder of OVCA1-1,BOV 1,BOV-1,BOV 1A,BOV-1A,BOV 1B,BOV-1B,BOV-1C,HSPC114,MDS014,

Blue Ice

20, 9

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.1M sodium chloride, 1mM DTT, 10% glycerol.

RBM8A is a member of the EJC(The exon junction complex) that is involved in mRNA export, cytoplasmic localization and nonsense mediated mRNA decay. This protein has the ability to communicate to the cytoplasm the processing history of the mRNA, including the position of the removed introns. Although it shuttles to the cytoplasm, it is predominantly detected in the nucleus and is colocalized with oskar mRNA at the posterior pole of the cell.

Source:
Recombinant corresponding to aa1-174 from human RBM8A, fused to His-tag at C-terminus expressed in E.coli.

AA Sequence:
MADVLDLHEA GGEDFAMDED GDESIHKLKE KAKKRKGRGF GSEEGSRARM REDYDSVEQD GDEPGPQRSV EGWILFVTGV HEEATEEDIH DKFAEYGEIK NIHLNLDRRT GYLKGYTLVE YETYKEAQAA MEGLNGQDLM GQPISVDWCF VRGPPKGKRR GGRRRSRSPD RRRRLEHHHH
HH

Molecular Weight:
~20.9kD (182aa), confirmed by MALDI-TOF

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

RNA Binding Motif Protein 8A, Recombinant, Human, aa1-174, His-Tag (RNA-binding Motif Protein 8A, RBM8a, RNA Binding Protein 8A, Binder of OVCA1 1, Binder of OVCA1-1, BOV 1, BOV-1, BOV 1A, BOV-1A, BOV 1B, BOV-1B, BOV-1C, HSPC114, MDS014, Ribonucleopr