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1437732 Item(s)

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  5. 24
Name PDF Type Clone Specific against Appl. Host Item no. Amount ✓ Price
PY-­60 Chemicals Other Blocking, IS, other DCC-DC57070-250mg

DCChemicals 		250 mg Login
Compare
VV116 (non-­deuterated) Chemicals Other non-label form of VV116.VV116 is an oral drug candidate of nucleoside analog against SARS-CoV-2. DCC-DC58060-100mg

DCChemicals 		100 mg Login
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VV116 (non-­deuterated) Chemicals Other non-label form of VV116.VV116 is an oral drug candidate of nucleoside analog against SARS-CoV-2. DCC-DC58060-250mg

DCChemicals 		250 mg Login
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VV116 (non-­deuterated) Chemicals Other non-label form of VV116.VV116 is an oral drug candidate of nucleoside analog against SARS-CoV-2. DCC-DC58060-1g

DCChemicals 		1 g Login
Compare
Cyclo(Gly-­L-­Pro) Chemicals Other Cyclo(Gly-(L)-Pro) shows immunostimulatory properties. Cyclo(Gly-l-Pro) exhibits potent inhibition of TNF-α release with the IC50 values of 4.5 ug/mL, respectively, it also exhibits significant diminution of IL-1β and IL-6 mRNA-expression levels and NO production. DCC-DC58002-1g

DCChemicals 		1 g Login
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LIPID C24 Chemicals Other C24 is a novel multiprotic ionizable lipid. C24 lipid nanoparticle (LNP) has a multistage protonation behavior resulting in greater endosomal protonation and greater translation compared to the standard reference MC3 LNP. C24 LNP also lower injection site DCC-DC57002-25mg

DCChemicals 		25 mg Login
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LIPID C24 Chemicals Other C24 is a novel multiprotic ionizable lipid. C24 lipid nanoparticle (LNP) has a multistage protonation behavior resulting in greater endosomal protonation and greater translation compared to the standard reference MC3 LNP. C24 LNP also lower injection site DCC-DC57002-50mg

DCChemicals 		50 mg Login
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LIPID C24 Chemicals Other C24 is a novel multiprotic ionizable lipid. C24 lipid nanoparticle (LNP) has a multistage protonation behavior resulting in greater endosomal protonation and greater translation compared to the standard reference MC3 LNP. C24 LNP also lower injection site DCC-DC57002-100mg

DCChemicals 		100 mg Login
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PF07104091(Tagtociclib) Chemicals Other ELISA, other DCC-DC53051-100mg

DCChemicals 		100 mg Login
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PHD-­1-­IN-­1 Chemicals Other PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC50 of 0.034 μM. PHD-1-IN-1 has a unique monodentate binding interaction with the active site Fe2+ ion and induces the formation of an “Arg367-out” pocket[ DCC-DC58150-100mg

DCChemicals 		100 mg Login
Compare
PHD-­1-­IN-­1 Chemicals Other PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC50 of 0.034 μM. PHD-1-IN-1 has a unique monodentate binding interaction with the active site Fe2+ ion and induces the formation of an “Arg367-out” pocket[ DCC-DC58150-250mg

DCChemicals 		250 mg Login
Compare
PHD-­1-­IN-­1 Chemicals Other PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC50 of 0.034 μM. PHD-1-IN-1 has a unique monodentate binding interaction with the active site Fe2+ ion and induces the formation of an “Arg367-out” pocket[ DCC-DC58150-1g

DCChemicals 		1 g Login
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Nicotinamide Riboside Chloride Chemicals Other other DCC-DC58307-1g

DCChemicals 		1 g Login
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DALDA Chemicals Other DALDA (H-Tyr-D-Arg-Phe-Lys-NH2) is a potent μ-opioid peptide agonist, affecting various patterns of locomotor activities. DCC-DC58305-100mg

DCChemicals 		100 mg Login
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DALDA Chemicals Other DALDA (H-Tyr-D-Arg-Phe-Lys-NH2) is a potent μ-opioid peptide agonist, affecting various patterns of locomotor activities. DCC-DC58305-250mg

DCChemicals 		250 mg Login
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DALDA Chemicals Other DALDA (H-Tyr-D-Arg-Phe-Lys-NH2) is a potent μ-opioid peptide agonist, affecting various patterns of locomotor activities. DCC-DC58305-1g

DCChemicals 		1 g Login
Compare
BMS-­986176 Chemicals Other AAK1-IN-1(BMS-986176) is a chemical probe for AAK1 and BIKE that potently targets the ATP-binding site (AAK1 Ki = 9.1 nM; BIKE Ki = 17 nM). Regarding kinase selectivity, only three kinases were observed to bind SGC-AAK1-1 within 30-fold of the KD of AAK1 in a KINOMEscan assay (DiscoverX) at 1 μM followed by KD determinations: RIOK1 (KD = 72 nM), RIOK3 (KD = 290 nM), and PIP5K1C (KD = 260 nM). In a live cell NanoBRET assay (Promega) SGC-AAK1-1 has potency for ectopically expressed full-length AAK1- and BIKE-Nluc fusion proteins (AAK1 IC50 = 230 nM; BIKE IC50 = 1.5 μM). DCC-DC58041-100mg

DCChemicals 		100 mg Login
Compare
BMS-­986176 Chemicals Other AAK1-IN-1(BMS-986176) is a chemical probe for AAK1 and BIKE that potently targets the ATP-binding site (AAK1 Ki = 9.1 nM; BIKE Ki = 17 nM). Regarding kinase selectivity, only three kinases were observed to bind SGC-AAK1-1 within 30-fold of the KD of AAK1 in a KINOMEscan assay (DiscoverX) at 1 μM followed by KD determinations: RIOK1 (KD = 72 nM), RIOK3 (KD = 290 nM), and PIP5K1C (KD = 260 nM). In a live cell NanoBRET assay (Promega) SGC-AAK1-1 has potency for ectopically expressed full-length AAK1- and BIKE-Nluc fusion proteins (AAK1 IC50 = 230 nM; BIKE IC50 = 1.5 μM). DCC-DC58041-250mg

DCChemicals 		250 mg Login
Compare
BMS-­986176 Chemicals Other AAK1-IN-1(BMS-986176) is a chemical probe for AAK1 and BIKE that potently targets the ATP-binding site (AAK1 Ki = 9.1 nM; BIKE Ki = 17 nM). Regarding kinase selectivity, only three kinases were observed to bind SGC-AAK1-1 within 30-fold of the KD of AAK1 in a KINOMEscan assay (DiscoverX) at 1 μM followed by KD determinations: RIOK1 (KD = 72 nM), RIOK3 (KD = 290 nM), and PIP5K1C (KD = 260 nM). In a live cell NanoBRET assay (Promega) SGC-AAK1-1 has potency for ectopically expressed full-length AAK1- and BIKE-Nluc fusion proteins (AAK1 IC50 = 230 nM; BIKE IC50 = 1.5 μM). DCC-DC58041-1g

DCChemicals 		1 g Login
Compare
PLX5622 hemifumarate Chemicals Other PLX-5622(PLX 5622) is a brain-penetrant inhibitor of the colony stimulating factor 1 receptor (CSF1R, IC50 = 0.016 µM). It is selective for CSF1R over FMS-related tyrosine kinase 3 (FLT3), Kit, Aurora C, and VEGFR2 (IC50s = 0.39, 0.86, 1, and 1.1 µM, respectively) and is greater than 100-fold selective for CSF1R over a panel of 230 kinases. PLX5622 (65 mg/kg) reduces the number of Iba-1+ cells, a marker of reduced microglia activation, in the dorsal horn of the spinal cord in a mouse model of neuropathic pain induced by partial ligation of the sciatic nerve. It also decreases macrophage levels of TNF-alpha and IL-1beta and infiltration into the sciatic nerve, as well as alleviates mechanical and cold allodynia in the same model. Dietary administration of PLX5622 (1, 200 ppm in chow) decreases the number of hippocampal microglia by 90%, as well as reduces the number and volume of retrosplenial and somatosensory cortical amyloid-beta (Abeta) plaques in the 5XFAD transgenic mouse model of Alzheimer's disease. DCC-DC59018-100mg

DCChemicals 		100 mg Login
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BTSA1.2 Chemicals Other IV DCC-DC59120-5mg

DCChemicals 		5 mg Login
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BTSA1.2 Chemicals Other IV DCC-DC59120-10mg

DCChemicals 		10 mg Login
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BTSA1.2 Chemicals Other IV DCC-DC59120-25mg

DCChemicals 		25 mg Login
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Nifeviroc Chemicals Other Nifeviroc is a CCR5 antagonist potentially for treatment of inflammatory responses to HIV type-1 infection DCC-DC55002-100mg

DCChemicals 		100 mg Login
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Nifeviroc Chemicals Other Nifeviroc is a CCR5 antagonist potentially for treatment of inflammatory responses to HIV type-1 infection DCC-DC55002-250mg

DCChemicals 		250 mg Login
Compare
Name Price
PY-­60 Login PY-60
Type Chemicals
Clone
Specific against Other
Appl. Blocking, IS, other
Host
Item no.
Amount 250 mg
Available
VV116 (non-­deuterated) Login VV116 (non-deuterated)
Type Chemicals
Clone
Specific against Other
Appl. non-label form of VV116.VV116 is an oral drug candidate of nucleoside analog against SARS-CoV-2.
Host
Item no.
Amount 100 mg
Available
VV116 (non-­deuterated) Login VV116 (non-deuterated)
Type Chemicals
Clone
Specific against Other
Appl. non-label form of VV116.VV116 is an oral drug candidate of nucleoside analog against SARS-CoV-2.
Host
Item no.
Amount 250 mg
Available
VV116 (non-­deuterated) Login VV116 (non-deuterated)
Type Chemicals
Clone
Specific against Other
Appl. non-label form of VV116.VV116 is an oral drug candidate of nucleoside analog against SARS-CoV-2.
Host
Item no.
Amount 1 g
Available
Cyclo(Gly-­L-­Pro) Login Cyclo(Gly-L-Pro)
Type Chemicals
Clone
Specific against Other
Appl. Cyclo(Gly-(L)-Pro) shows immunostimulatory properties. Cyclo(Gly-l-Pro) exhibits potent inhibition of TNF-α release with the IC50 values of 4.5 ug/mL, respectively, it also exhibits significant diminution of IL-1β and IL-6 mRNA-expression levels and NO production.
Host
Item no.
Amount 1 g
Available
LIPID C24 Login LIPID C24
Type Chemicals
Clone
Specific against Other
Appl. C24 is a novel multiprotic ionizable lipid. C24 lipid nanoparticle (LNP) has a multistage protonation behavior resulting in greater endosomal protonation and greater translation compared to the standard reference MC3 LNP. C24 LNP also lower injection site
Host
Item no.
Amount 25 mg
Available
LIPID C24 Login LIPID C24
Type Chemicals
Clone
Specific against Other
Appl. C24 is a novel multiprotic ionizable lipid. C24 lipid nanoparticle (LNP) has a multistage protonation behavior resulting in greater endosomal protonation and greater translation compared to the standard reference MC3 LNP. C24 LNP also lower injection site
Host
Item no.
Amount 50 mg
Available
LIPID C24 Login LIPID C24
Type Chemicals
Clone
Specific against Other
Appl. C24 is a novel multiprotic ionizable lipid. C24 lipid nanoparticle (LNP) has a multistage protonation behavior resulting in greater endosomal protonation and greater translation compared to the standard reference MC3 LNP. C24 LNP also lower injection site
Host
Item no.
Amount 100 mg
Available
PF07104091(Tagtociclib) Login PF07104091(Tagtociclib)
Type Chemicals
Clone
Specific against Other
Appl. ELISA, other
Host
Item no.
Amount 100 mg
Available
PHD-­1-­IN-­1 Login PHD-1-IN-1
Type Chemicals
Clone
Specific against Other
Appl. PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC50 of 0.034 μM. PHD-1-IN-1 has a unique monodentate binding interaction with the active site Fe2+ ion and induces the formation of an “Arg367-out” pocket[
Host
Item no.
Amount 100 mg
Available
PHD-­1-­IN-­1 Login PHD-1-IN-1
Type Chemicals
Clone
Specific against Other
Appl. PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC50 of 0.034 μM. PHD-1-IN-1 has a unique monodentate binding interaction with the active site Fe2+ ion and induces the formation of an “Arg367-out” pocket[
Host
Item no.
Amount 250 mg
Available
PHD-­1-­IN-­1 Login PHD-1-IN-1
Type Chemicals
Clone
Specific against Other
Appl. PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC50 of 0.034 μM. PHD-1-IN-1 has a unique monodentate binding interaction with the active site Fe2+ ion and induces the formation of an “Arg367-out” pocket[
Host
Item no.
Amount 1 g
Available
Nicotinamide Riboside Chloride Login Nicotinamide Riboside Chloride
Type Chemicals
Clone
Specific against Other
Appl. other
Host
Item no.
Amount 1 g
Available
DALDA Login DALDA
Type Chemicals
Clone
Specific against Other
Appl. DALDA (H-Tyr-D-Arg-Phe-Lys-NH2) is a potent μ-opioid peptide agonist, affecting various patterns of locomotor activities.
Host
Item no.
Amount 100 mg
Available
DALDA Login DALDA
Type Chemicals
Clone
Specific against Other
Appl. DALDA (H-Tyr-D-Arg-Phe-Lys-NH2) is a potent μ-opioid peptide agonist, affecting various patterns of locomotor activities.
Host
Item no.
Amount 250 mg
Available
DALDA Login DALDA
Type Chemicals
Clone
Specific against Other
Appl. DALDA (H-Tyr-D-Arg-Phe-Lys-NH2) is a potent μ-opioid peptide agonist, affecting various patterns of locomotor activities.
Host
Item no.
Amount 1 g
Available
BMS-­986176 Login BMS-986176
Type Chemicals
Clone
Specific against Other
Appl. AAK1-IN-1(BMS-986176) is a chemical probe for AAK1 and BIKE that potently targets the ATP-binding site (AAK1 Ki = 9.1 nM; BIKE Ki = 17 nM). Regarding kinase selectivity, only three kinases were observed to bind SGC-AAK1-1 within 30-fold of the KD of AAK1 in a KINOMEscan assay (DiscoverX) at 1 μM followed by KD determinations: RIOK1 (KD = 72 nM), RIOK3 (KD = 290 nM), and PIP5K1C (KD = 260 nM). In a live cell NanoBRET assay (Promega) SGC-AAK1-1 has potency for ectopically expressed full-length AAK1- and BIKE-Nluc fusion proteins (AAK1 IC50 = 230 nM; BIKE IC50 = 1.5 μM).
Host
Item no.
Amount 100 mg
Available
BMS-­986176 Login BMS-986176
Type Chemicals
Clone
Specific against Other
Appl. AAK1-IN-1(BMS-986176) is a chemical probe for AAK1 and BIKE that potently targets the ATP-binding site (AAK1 Ki = 9.1 nM; BIKE Ki = 17 nM). Regarding kinase selectivity, only three kinases were observed to bind SGC-AAK1-1 within 30-fold of the KD of AAK1 in a KINOMEscan assay (DiscoverX) at 1 μM followed by KD determinations: RIOK1 (KD = 72 nM), RIOK3 (KD = 290 nM), and PIP5K1C (KD = 260 nM). In a live cell NanoBRET assay (Promega) SGC-AAK1-1 has potency for ectopically expressed full-length AAK1- and BIKE-Nluc fusion proteins (AAK1 IC50 = 230 nM; BIKE IC50 = 1.5 μM).
Host
Item no.
Amount 250 mg
Available
BMS-­986176 Login BMS-986176
Type Chemicals
Clone
Specific against Other
Appl. AAK1-IN-1(BMS-986176) is a chemical probe for AAK1 and BIKE that potently targets the ATP-binding site (AAK1 Ki = 9.1 nM; BIKE Ki = 17 nM). Regarding kinase selectivity, only three kinases were observed to bind SGC-AAK1-1 within 30-fold of the KD of AAK1 in a KINOMEscan assay (DiscoverX) at 1 μM followed by KD determinations: RIOK1 (KD = 72 nM), RIOK3 (KD = 290 nM), and PIP5K1C (KD = 260 nM). In a live cell NanoBRET assay (Promega) SGC-AAK1-1 has potency for ectopically expressed full-length AAK1- and BIKE-Nluc fusion proteins (AAK1 IC50 = 230 nM; BIKE IC50 = 1.5 μM).
Host
Item no.
Amount 1 g
Available
PLX5622 hemifumarate Login PLX5622 hemifumarate
Type Chemicals
Clone
Specific against Other
Appl. PLX-5622(PLX 5622) is a brain-penetrant inhibitor of the colony stimulating factor 1 receptor (CSF1R, IC50 = 0.016 µM). It is selective for CSF1R over FMS-related tyrosine kinase 3 (FLT3), Kit, Aurora C, and VEGFR2 (IC50s = 0.39, 0.86, 1, and 1.1 µM, respectively) and is greater than 100-fold selective for CSF1R over a panel of 230 kinases. PLX5622 (65 mg/kg) reduces the number of Iba-1+ cells, a marker of reduced microglia activation, in the dorsal horn of the spinal cord in a mouse model of neuropathic pain induced by partial ligation of the sciatic nerve. It also decreases macrophage levels of TNF-alpha and IL-1beta and infiltration into the sciatic nerve, as well as alleviates mechanical and cold allodynia in the same model. Dietary administration of PLX5622 (1, 200 ppm in chow) decreases the number of hippocampal microglia by 90%, as well as reduces the number and volume of retrosplenial and somatosensory cortical amyloid-beta (Abeta) plaques in the 5XFAD transgenic mouse model of Alzheimer's disease.
Host
Item no.
Amount 100 mg
Available
BTSA1.2 Login BTSA1.2
Type Chemicals
Clone
Specific against Other
Appl. IV
Host
Item no.
Amount 5 mg
Available
BTSA1.2 Login BTSA1.2
Type Chemicals
Clone
Specific against Other
Appl. IV
Host
Item no.
Amount 10 mg
Available
BTSA1.2 Login BTSA1.2
Type Chemicals
Clone
Specific against Other
Appl. IV
Host
Item no.
Amount 25 mg
Available
Nifeviroc Login Nifeviroc
Type Chemicals
Clone
Specific against Other
Appl. Nifeviroc is a CCR5 antagonist potentially for treatment of inflammatory responses to HIV type-1 infection
Host
Item no.
Amount 100 mg
Available
Nifeviroc Login Nifeviroc
Type Chemicals
Clone
Specific against Other
Appl. Nifeviroc is a CCR5 antagonist potentially for treatment of inflammatory responses to HIV type-1 infection
Host
Item no.
Amount 250 mg
Available

1437732 Item(s)

per page

Page:
  1. 20
  2. 21
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  4. 23
  5. 24
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