Recombinant Human C-ets-1 Protein

The proto-oncogene c-Ets-1 is a transcription factor known to regulate expression of a number of genes involved in extracellular matrix remodeling, control numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. Ets-1 interacts with the urokinase-type plasminogen activator gene enhancer and with the promoters of stromelysins-1 and collagenase-1 gene which may implicate it in this process.
The conserved ETS domain inside these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes.

Escherichia Coli.

ETS1 protein in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.

Store vial at -20C to -80C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.