Comparison

Recombinant HTLV-1 p24 Core European Partner

Item no. hiv-108-1mg
Manufacturer ProSpec
Amount 1mg
Category
Type Viral Antigens
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352202
Similar products HTLV-1 p24c
Available
Introduction
Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).
Description
The E.Coli derived recombinant protein contains the full-length sequence of HTLV-I p24, spanning all of p24.
The protein contains 214 amino acids having an Mw of 24kDa.
Formulation
50mM NaPO4 pH 6.0, containing 1mM DTT & 1mM EDTA.
Purity
HTLV-1 p24 protein is >95% pure as determined by 10% PAGE (coomassie staining) and RP-HPLC.
Usage
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Specificity
Immunoreactive with all sera of HTLV-1 infected individuals.
Purification Method
HTLV-1 p24 was purified by proprietary chromatographic technique.
Storage
HTLV-1 p24 although stable at 4C for 1 week, should be stored below -18C.
Please prevent freeze thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1mg
Available: In stock
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