Desmin

Item no.	ARP-03-62016
Manufacturer	American Research Products
Amount	250 ug
Category	Peptides & Proteins Native Proteins
Type	Proteins Native
Specific against	other
Purity	> 95%, SDS-PAGE
Citations	Geisler, N. and Weber, K. (1980) Eur. J. Biochem. 111: 425 ff Hatzfeld M. and Franke W.W. (1985). J. Cell Biol. 101, 1826-1841 Hatzfeld M. et al. (1987). J. Mol. Biol. 197, 237-255
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	Recombinant Desmin from Escherichia coli
Background	The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21
Form	Lyophilized, salt balanced.
Working Dilution	Optimal dilution should be determined by user
Storage	4C (lyophilized), at -20C (solution, aliquot)
References	Geisler, N. and Weber, K. (1980) Eur. J. Biochem. 111: 425 ff Hatzfeld M. and Franke W.W. (1985). J. Cell Biol. 101, 1826-1841 Hatzfeld M. et al. (1987). J. Mol. Biol. 197, 237-255
Reconstitution	When reconstituted with 175ul H20 dist, a final solution volume of 250 ul will contain 30mM Tris/HCl, pH 8, 9.5M urea, 2mM DTT, 2mM EDTA, 10mM Methylammoniumchloride, with a protein concentration of 1mg/ml
Purity	>, 95%, SDS-PAGE
Source	Escherichia coli
Molecular Weight	53539.6 (calculated from sequence), 55, 000 (SDS)
Isoelectric Point	Pi 5.16

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 ug

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Delivery expected until 12/18/2025

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