Desmin

Item no.	ARP-03-62205
Manufacturer	American Research Products
Amount	100 ug
Category	Peptides & Proteins Native Proteins
Type	Proteins Native
Specific against	other
Purity	> 98%, SDS-PAGE
Citations	Geisler, N. and Weber, K. (1980) Eur. J. Biochem. 111: 425 ff Hatzfeld, M. &, Franke, WW (1985) J. Cell Biol. 101: 1826-1841 Hatzfeld, M. et al. (1987) J. Mol. Biol. 197: 237-255
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CSM1, CSM2, LGMD2R
Available
Description	Desmin purified from chicken gizzard
Background	This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
Form	Lyophilized, salt balanced.
Working Dilution	Optimal dilution should be determined by user
Storage	4C (lyophilized), at -20C (solution, aliquot)
Synonyms	CSM1, CSM2, LGMD2R
References	Geisler, N. and Weber, K. (1980) Eur. J. Biochem. 111: 425 ff Hatzfeld, M. &, Franke, WW (1985) J. Cell Biol. 101: 1826-1841 Hatzfeld, M. et al. (1987) J. Mol. Biol. 197: 237-255
Reconstitution	When reconstituted with 80ul H20 dist, a final solution volume of 100 ul will contain 10mM sodium phosphate, pH 7.5, 2mM DTT, 6M urea, 1mM EDTA with a protein concentration of 1mg/ml (according to Bradford protein determination)
Purity	>, 98%, SDS-PAGE
Source	Chicken Gizzard
Molecular Weight	53
Isoelectric Point	pI 5.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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