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Neurofilament 200

Neurofilament 200

Item no.	ARP-03-62210
Manufacturer	American Research Products
Amount	100 ug
Category	Peptides & Proteins Native Proteins
Type	Proteins Native
Specific against	other
Purity	> 98%, SDS-PAGE
Citations	Dahl, D.et al. (1982). Analyt. Biochem. 126: 165ff Weber, K et al. (1983) Quant. Biol. 48: 717ff
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	NFH
Available
Description	Neurofilament 200 purified from bovine spinal cord
Background	Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.
Form	Lyophilized, salt balanced.
Working Dilution	Optimal dilution should be determined by user
Storage	4C (lyophilized), at -20C (solution, aliquot)
Synonyms	NFH
References	Dahl, D.et al. (1982). Analyt. Biochem. 126: 165ff Weber, K et al. (1983) Quant. Biol. 48: 717ff
Reconstitution	When reconstituted with 80ul H20 dist, a final solution volume of 100 ul will contain 10mM sodium phosphate, pH 7.5, 2mM DTT, 6M urea, 1mM EDTA with a protein concentration of 1mg/ml (according to Bradford protein determination)
Purity	>, 98%, SDS-PAGE
Source	Bovine spinal cord
Molecular Weight	200
Isoelectric Point	pI 5.5

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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