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Cathepsin D

Cathepsin D

Item no.	ARP-12-7609
Manufacturer	American Research Products
Amount	25 ug
Category	Peptides & Proteins Native Proteins
Type	Proteins Native
Specific against	other
Purity	> 95% by SDS-PAGE
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Description	Cathepsin D is an estrogen-regulated protein associated with tissue breakdown. Levels of cathepsin D have been positively correlated with recurring breast cancers of both node negative and node positive types. Additionally, cathepsin D has been associated with amyloid formation in Alzheimer's p, aques. As cathepsin D activity is increased by cigarette smoke, the enzyme may contribute to lung tissue damage in smokers.
Form	Purified, lyophilized
Storage	2-8C for immediate use, or at -20C (aliquot)
Purity	>, 95% by SDS-PAGE
Source	Human liver. Nonreactive and negative for HBsAg, anti-HCV, anti-HBc, and anti-HIV by FDA-required tests
Molecular Weight	42, 000 Daltons
Biological Activity	>, 300 units/mg protein. One unit is defined as the amount of enzyme that digests hemoglobin releasing peptides which are soluble in 10% TCA. The reaction is measured by an increase of an A280 of 1.0 per 60 minutes at 37AC. Substrate: acid denatured hemoglobin (0.2% in reaction mixture). Buffer: 100mM formate, pH 7.3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 ug

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Delivery expected until 12/18/2025

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