Comparison

Immunoglobulin G, Fc (IgG, Fc)

Item no. ARP-13-3033
Manufacturer American Research Products
Amount 200 ug
Category
Type Proteins Native
Specific against other
Purity Fractionation and DEAE Chromatography, Fc fragments were produced by papain digestion and affinity chromatography
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IgG
Available
Description
Purified Native Human Immunoglobulin G IgG-FC, Human Plasma, FC Fragment.
Background
Immunoglobulin G (IgG) is an antibody isotype. It is a protein complex composed of four peptide chains - two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers. Each IgG has two antigen binding sites. Representing approximately 75% of serum immunoglobulins in humans, IgG is the most abundant antibody isotype found in the circulation. IgG molecules are synthesized and secreted by plasma B cells.
Form
Purified IgG, in PBS, pH 7.2, containing 0.1% sodium azide
Storage
2-8C
Synonyms
IgG
Concentration
1 mg/ml, E280 nm=1.4
Purity
  • Fractionation and DEAE Chromatography, Fc fragments were
  • produced by papain digestion and affinity chromatography
Source
  • Normal human Serum. Blood sample from donors was tested and found negative
  • for HBsAg, HIV-1&, 2 antibodies, HCV and Syphilis
Notes
Because no test method can offer complete assurance that products derived from human source will not transmit infectious agents, it is recommended that this product be handled with the same precautions used for patient specimens.
Molecular Weight
50000
Biological Activity
The IgG fc fragment does not bind antigen, however, it does contain the classic antigenic determinants and biological activity with respect to cytotrophic reactions, binding of complement and catabolic rate control

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 ug
Available: In stock
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