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Immunoglobulin M (IgM), m Chain

Immunoglobulin M (IgM), m Chain

Item no.	ARP-13-3035-2
Manufacturer	American Research Products
Amount	200 ug
Category	Peptides & Proteins Native Proteins
Type	Proteins Native
Specific against	other
Purity	Single arc by IEP against antisera to whole human serum and antisera to IgM, mu chain specific. No reaction by IEP to antisera to kappa or lambda
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IgM
Available
Description	IgM heavy chain (m chain) consists of 576 amino acids, there are five chains in each IgM molecule. IgM heavy chain is purified by reducing the disulfide bond connecting it to the IgM kappa and lambda light chains. IgM m chain is more highly conserved across different species than is IgG, IgA, or kappa and lambda light chain.
Background	Immunoglobulin M (IgM) is a basic antibody that is produced by B cells. IgM is by far the physically largest antibody in the human circulatory system. IgM forms polymers where multiple immunoglobulins are covalently linked together with disulfide bonds, mostly as a pentamer but also as a hexamer. IgM has a molecular mass of approximately 970 kDa (in its pentamer form). Because each monomer has two antigen binding sites, a pentameric IgM has 10 binding sites.
Form	Purified, in 1.0 M Acetic acid
Storage	-20C (aliquot)
Synonyms	IgM
Purity	Single arc by IEP against antisera to whole human serum and antisera to IgM, mu chain specific. No reaction by IEP to antisera to kappa or lambda
Source	Human plasma. Blood sample from donors was tested and found negative for HBsAg, HIV-1&, 2 antibodies, HCV and Syphilis
Notes	Because no test method can offer complete assurance that products derived from human source will not transmit infectious agents, it is recommended that this product be handled with the same precautions used for patient specimens.
Molecular Weight	75000

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ug

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Delivery expected until 12/18/2025

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