Comparison

MIF/Macrophage migration inhibitory factor

Item no. E21-H33
Manufacturer Enogene
Amount 10 ug
Category
Type Proteins
Format Liquid
Specific against Human (Homo sapiens)
Host E.coli
Purity Greater than 95% as determined by reducing SDS-PAGE.
Dry ice Yes
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Macrophage migration inhibitory factor,MIF,MMIF,Glycosylation-inhibiting factor,GLIF,L-dopachrome tautomerase,Phenylpyruvate tautomerase
Available
Shipping Temperature
The product is shipped on dry ice/ice packs.
Dry Ice/ice packs
Storage Conditions
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
Background
Human MIF is a 12.5 kDa, 115 amino acid (aa) nonglycosylated polypeptide that is synthesized without asignal sequence .Secretion occurs nonclassically via an ABCA1 transporter.Pro-inflammatory cytokine.Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites ofinflammation suggests a role as mediator in regulating the function of acrophages in host defense.Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase anddopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clearwhether the tautomerase activity has any physiological relevance, and whether it is important for cytokineactivity.
Description
Recombinant Human Macrophage migration inhibitory factor is produced by our E.coli expression system and the target gene encoding Met1-Ala115 is expressed.
Endotoxin
Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Formulation Description
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 20% Glycerol, pH7.4.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
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