Comparison

Human FGF-10 / KGF 2 Protein, His Tag European Partner

Item no. FG0-H5145-100ug
Manufacturer ACROBiosystems
Amount 100 ug
Quantity options 100 ug 200 ug x 5
Category
Type Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag Unconjugated
Purity 95%
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias FGF-10,Fibroblast growth factor 10,Keratinocyte growth factor 2
Shipping Condition Room temperature
Available
Manufacturer - Category
Protein
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
21.2 kDa
Manufacturer - Format
Powder
Description
Human FGF-10 Protein, His Tag (FG0-H5145) is expressed from E. coli cells. It contains AA Gln 38 - Ser 208 (Accession # O15520-1).
Background
Fibroblast Growth Factor 10 (FGF 10) is an evolutionary conserved secreted growth factor mediating mostly mesenchymal to epithelial signaling. FGF 10 belongs to the FGF 7 subfamily and shares similar biochemical and amino acid sequences with its constituent members (FGF3, FGF 7 and FGF 22). As a paracrine FGF, FGF 10 elicits its biological responses by activating the fibroblast growth factor receptor 2b (FGF R 2b), is crucial for governing proximal distal outgrowth as well as patterning and acts upstream of the known apical ectodermal ridge (AER) marker FGF 8. FGF10 is also implicated in pancreatic cancer, and that overexpression of FGFR2b is associated with metastatic invasion.
Molecule
FGF-10
Exp Region
Gln 38 - Ser 208
Characteristics
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 21.2 kDa. The protein migrates as 27 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin
0.1 EU per μg
Buffer
20 mM MOPS, 200 mM NaCl, 100 mM Na2SO4, 1mM DTT, pH 7.0
Stability
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: Out of stock
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