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GDNF, human recombinant

GDNF, human recombinant

Item no.	ICO-P-103-100-50ug
Manufacturer	Icosagen
Amount	50ug
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Human (Homo sapiens)
Host	Mammalian cell
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Glial cell line-derived neurotrophic factor, Astrocyte-derived trophic factor (ATF)
Available
Background	GDNF is an important member of the GDNF family of ligands. Four members of nurotrophic factors beloning to the GDNF family of ligands : glial cell line-derived neurotrophic factor (GDNF), neurturin (NRTN), artemin (ARTN), and persephin (PSPN). GDNF is important in the promotion of the survival of dopaminergic neurons. The recombinant form of this protein promotes the survival and differentiation of dopaminergic neurons in culture, and is able to prevent apoptosis of motor neurons induced by axotomy.
Buffer	PBS pH 7.4
Concentration	0.96 mg/ml
Endotoxine	Less than 1EU/mg of protein as determined by LAL method
Molecular Weight	Mature GDNF, Approximately 15 kDa, a single non-glycosylated polypeptide chain containing 118 amino acids
Purification	Purified by ion-exchange chromatography and gel-filtration from serum-free CHO growth media. Protein is sterile-filtrated through 0.22 um filter
Storage	Store at -70C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles
Uniprot ID	P39905

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 9/25/2025

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