« Back
Home /
Recombinant Human EPHB1 Protein, Fc Tag

Recombinant Human EPHB1 Protein, Fc Tag

Item no.	KMD-KMH1036-50ug
Manufacturer	KMD Bioscience
Amount	50 ug
Category	Oncology Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Recombinant Proteins Obesity By Organ Colorectal Cancer
Type	Proteins Recombinant
Specific against	Human (Homo sapiens)
Host	Mammalian cell
Conjugate/Tag	Fc
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ELK, NET, Hek6, EPHT2, EPH receptor B1
Available
Molecular Name	EPHB1
Source	This protein contains the human EPHB1(Met18-Pro540) was fused with the C-terminal Fc Tag and expressed in Mammalian cells.
Uniprot Accession	P54762
Purity	>=90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Buffer	PBS
Purification	Protein A/G
Predicted Molecular Weight	82.53kDa
Background	EPHB1 is a member of the Eph family of receptor tyrosine kinases. Ligand-activated EPHB1 forms a signaling complex with Nck, paxillin, and focal adhesion kinase and induces tyrosine phosphorylation of paxillin in a c-Src-dependent manner to promote cell migration. In addition, activated EPHB1 recruits the adaptor proteins Grb2 and p52Shc and promotes p52Shc and c-Src tyrosine phosphorylation as well as MAPK/extracellular signal-regulated kinase (ERK) activation. Expression of dominant-negative c-Src significantly reduced EPHB1-dependent ERK1/2 activation and chemotaxis.
Storage	Store the product under sterile conditions after opening at -20C to -80C for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 50 ug

available

Delivery expected until 9/18/2025

Express Delivery: Save 30 days

Compare

Add to wishlist

Get an offer