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Recombinant Human IGFBP-4/IGFBP4 Protein, His Tag

Recombinant Human IGFBP-4/IGFBP4 Protein, His Tag

Item no.	KMD-KMH1259-50ug
Manufacturer	KMD Bioscience
Amount	50 ug
Category	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Peptides & Proteins Recombinant Proteins Endocrine Regulation of Lipid Metabolism
Type	Proteins Recombinant
Specific against	Human (Homo sapiens)
Host	Mammalian cell
Conjugate/Tag	His
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	BP-4, IBP4, IGFBP-4, HT29-IGFBP, insulin like growth factor binding protein 4
Available
Molecular Name	IGFBP4
Source	This protein contains the human IGFBP4(Asp22-Glu258) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Uniprot Accession	P22692
Purity	>=90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Buffer	PBS
Purification	Protein A/G
Predicted Molecular Weight	26.07kDa
Background	IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP4 is the major IGF-BP produced by osteoblasts, and is also found in the epidermis, ovarian follicles, and other tissues. IGF-BP4 inhibits the activity of IGF-I and IGF-II by binding in a manner that results in the formation of complexes with reduced ability to signal through cell surface IGF receptors. IGF-BP4 can inhibit the growth of chick pelvis cartilage and HT29 colon adenocarcinoma cells by blocking the mitogenic actions of IGFs, and has also been shown to reduce colony formation by colorectal cancer cells via an IGF independent pathway.
Storage	Store the product under sterile conditions after opening at -20C to -80C for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 9/18/2025

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