Recombinant Human CD8A Protein, His Tag

CD8A

P01732

< 1.0 EU per ug of the protein as determined by the LAL method.

Protein A/G

Cluster of Differentiation 8 alpha chain (CD8A), also known as Cluster of Differentiation 8a (CD8A), is a single-pass type I membrane protein. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.

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