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Recombinant Human Activin RIB/ALK-4/ACVR1B Protein, His Tag

Recombinant Human Activin RIB/ALK-4/ACVR1B Protein, His Tag

Item no.	KMD-KMH628-50ug
Manufacturer	KMD Bioscience
Amount	50 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Human (Homo sapiens)
Host	Mammalian cell
Conjugate/Tag	His
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ALK4, SKR2, ACTRIB, ACVRLK4, activin A receptor type 1B
Available
Molecular Name	ACVR1B
Source	This protein contains the human ACVR1B(Ser24-Glu126) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Uniprot Accession	P36896
Purity	>=90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Buffer	PBS
Purification	Protein A/G
Predicted Molecular Weight	11.33kDa
Background	Activin RIB, also known as ALK4, is a glycosylated type I receptor in the superfamily of TGF-beta serine/threonine kinase receptors. Activin RIB associates with Activin RIIB to form a receptor complex for activin and inhibin molecules. These ligands bind to Activin RIIB which then associates with and phosphorylates the cytoplasmic domain of Activin RIB to initiate signal transduction.Within the ECD, human Activin RIB shares 93% and 95% aa sequence identity with mouse and rat Activin RIB, respectively. It shares 25% - 35% aa sequence identity with other human type I receptors Activin RIA, Activin RIC, BMPR-IA, BMPR-IB, and TGF-beta R1.
Storage	Store the product under sterile conditions after opening at -20C to -80C for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 9/18/2025

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