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Recombinant Human CDKN1B Protein, His Tag

Recombinant Human CDKN1B Protein, His Tag

Item no.	KMD-KMH854-50ug
Manufacturer	KMD Bioscience
Amount	50 ug
Category	Oncology Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Hematology Lymphoma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Apoptosis Senescence Proliferation By Organ Lung Cancer Bladder Cancer
Type	Proteins Recombinant
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	His
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	KIP1, MEN4, CDKN4, MEN1B, P27KIP1, cyclin dependent kinase inhibitor 1B
Available
Molecular Name	CDKN1B
Source	This protein contains the human CDKN1B(Met1-Thr198) was fused with the N-terminal His Tag and expressed in E. coli.
Uniprot Accession	Q6I9V6
Purity	>=90% as determined by SDS-PAGE
Endotoxin	Please contact our customer service for more information.
Buffer	PBS
Purification	Protein A/G
Predicted Molecular Weight	21.78kDa
Background	KIP1 (cyclin-dependent kinase inhibitor 1B) is a kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation. Many tumorigenic processes modulate cell-cycle progression by regulating the levels of the cyclin-dependent kinase inhibitor KIP1. KIP1 binds to and inhibits cyclinE-Cdk2 complex, cyclinA-CDK2 and cyclinD1-CDK4. The phosphorylation- and ubiquitination-dependent proteolysis of KIP1 is implicated in control of the G1-S transition in the cell cycle. KIP1 is critical for retinoblastoma protein (Rb)-induced cellular proliferative senescence.
Storage	Store the product under sterile conditions after opening at -20C to -80C for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 9/18/2025

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