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Recombinant Mouse Cadm1 Protein, Fc Tag

Recombinant Mouse Cadm1 Protein, Fc Tag

Item no.	KMD-MOP2084-50ug
Manufacturer	KMD Bioscience
Amount	50 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Neural Adhesion Molecules By Cell Type Blastoma Carcinoma Hematology Myeloma Sarcoma Peptides & Proteins Recombinant Proteins By Organ Lung Cancer
Type	Proteins Recombinant
Specific against	Mouse (Murine, Mus musculus)
Host	Mammalian cell
Conjugate/Tag	Fc
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Bl2, ST17, Igsf4, Necl2, RA175, Tslc1, Igsf4a, RA175A, RA175B, RA175C, RA175N, SgIGSF, SynCam, AI987920, 2900073G06Rik, 3100001I08Rik, cell adhesion molecule 1
Available
Molecular Name	Cadm1
Source	This protein contains the mouse Cadm1(Gln48-His388) was fused with the C-terminal Fc Tag and expressed in Mammalian cells.
Uniprot Accession	Q8R5M8
Purity	>=90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Buffer	PBS
Purification	Protein A/G
Predicted Molecular Weight	62.51kDa
Background	Cadm1 is a 75 kDaimmunoglobulin superfamily protein that mediates calcium-independent adhesiveinteractions, either homophilic or heterophilic with CRTAM (classI-restricted T cell-associated molecule), Necl1 (SynCAM3) or Nectin3.Alternate names for Cadm1 reflect its activities. As Cadm1, it isdownregulated in onsmall cell lung cancer. This may allow evasion ofantitumor responses, since Cadm1 interaction with CRTAM on activated NK andCD8+ T cells stimulates cytotoxicity and upregulates IFN-gamma production.
Storage	Store the product under sterile conditions after opening at -20C to -80C for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 9/18/2025

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