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Recombinant Mouse Dr6/Tnfrsf21 Protein, His & Fc Tag

Recombinant Mouse Dr6/Tnfrsf21 Protein, His & Fc Tag

Item no.	KMD-MOP2131-100ug
Manufacturer	KMD Bioscience
Amount	100 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Aging & Neurological Disorders By Cell Type Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis
Type	Proteins Recombinant
Specific against	Mouse (Murine, Mus musculus)
Host	Mammalian cell
Conjugate/Tag	His; Fc
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DR6, TR7, R74815, AA959878, tumor necrosis factor receptor superfamily, member 21
Available
Molecular Name	Tnfrsf21
Source	This protein contains the mouse Tnfrsf21(Gln42-His349) was fused with the C-terminal His, Fc Tag and expressed in Mammalian cells.
Uniprot Accession	Q9EPU5
Purity	>=90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Buffer	PBS
Purification	Protein A/G
Predicted Molecular Weight	58.88kDa
Background	Death receptor-6 (DR6), a member of the death domain-containing TNFR superfamily, is highly expressed in lymphoid tissues and regulated upon lymphocyte activation. Targeted disruption of DR6 results in enhanced CD4(+) T cell proliferation and T helper 2 differentiation in vitro. DR6 contains an extracellular region and an intracellular region; the intracellular region harbors a death domain that is critical for transduction of apoptotic signals. DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kappaB and JNK.
Storage	Store the product under sterile conditions after opening at -20C to -80C for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 9/18/2025

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