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TRAIL Receptor-1 (NT) Blocking Peptide - 50 µg

TRAIL Receptor-1 (NT) Blocking Peptide - 50 µg

Item no.	LEIN-D278-50ug
Manufacturer	Leinco Technologies
Amount	50 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes By Cell Type Peptides & Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Peptides
Type	Peptides
Specific against	Human (Homo sapiens)
Citations	1. Yoo, NJ. et al. (2001) Oncogene 20: 399 2. Eberle, J. et al. (2005) J Investigative Dermatol. 125: 1010 3. Rimm, D. et al. (2005) Clin Cancer Research 11
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Shipping Condition	Room temperature
Available
Manufacturer - Category	Control Peptides
Manufacturer - Targets	TNF-Related Apoptosis Inducing Ligand Receptor-1
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	Store this peptide in working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Product Description	Tumor necrosis factor-related apoptosis-inducing ligand Receptor 1 (TRAIL-R1) is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.1 The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells.2
Background	Tumor necrosis factor-related apoptosis-inducing ligand Receptor 1 (TRAIL-R1) is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.¹ The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells.²
PubMed	TNF-Related Apoptosis Inducing Ligand Receptor-1
Amino acid location	This peptide sequence is located at amino acids 1 to 20 of Human DR4 protein.
Concentration	0.2 mg/ml
Formulation	This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Blocking Peptide, TNF-Related Apoptosis Inducing Ligand Receptor-1, TNFRSF10A, APO2, CD261, DR4, MGC9365, TRAIL R-1, Human, TRAIL Receptor-1 (NT) Blocking Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/11/2025

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