Comparison

PTK7 / CCK4 Recombinant Protein

Item no. PRS-11-124-0.1mg
Manufacturer ProSci
Amount 0.1 mg
Category
Type Proteins Recombinant
Format Lyophilized
Applications WB
Specific against other
Conjugate/Tag HIS
Purity >95% as determined by SDS-PAGE.
Sequence Ala 31 - Thr 704
Citations Won-Sik Shin, et al. Biochem Biophys Res Commun. 2008. 371(4):793-8.
Thomas Prebet, et al. Blood. 2010. 116(13):2315-23.
Vladislav S Golubkov, et al. J Biol Chem. 2010. 285(46):35740-9.
NCBI PTK7
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias PTK7,CCK4,CCK-4,Tyrosine-protein kinase-like 7,Protein-tyrosine kinase 7,Protein-tyrosine kinase 7
Available
Manufacturer - Applications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 76.5 kDa. The protein migrates as 90-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Storage Conditions
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
76.5 kDa
Background
PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
Buffer
PBS, pH7.4
NCBI Official Name
proteintyrosinekinase7(inactive)
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.1 mg
Available: In stock
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