« Back
Home /
CD45 / PTPRC Recombinant Protein

CD45 / PTPRC Recombinant Protein

Item no.	PRS-11-133-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Oncology Neuroscience Neural Lineage Markers By Cell Type Carcinoma Hematology Leukemia Peptides & Proteins Recombinant Proteins Western Blot Progenitor Markers
Type	Proteins Recombinant
Format	Lyophilized
Applications	WB
Specific against	other
Conjugate/Tag	HIS
Purity	>90% as determined by SDS-PAGE.
Sequence	Gln 26 - Lys 577
Citations	Shen F.W. et al. Immunogenetics 24 (1986) 146–149. Charbonneau H. et al. Proc. Natl. Acad. Sci. U. S. A. 85 (1988) 7182–7186. Rheinländer A. et al. Immunol Lett. 2018 Apr; 196:22-32.
NCBI	PTPRC
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD45,PTPRC,L-CA,T200
Available
Manufacturer - Applications	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 62.8 kDa. The protein migrates as 120-170 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Storage Conditions	Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Molecular Weight	62.8 kDa
Background	CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.
Buffer	PBS, pH7.4
NCBI Official Name	proteintyrosinephosphatasereceptortypeC
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 0.1 mg

available

Delivery expected until 10/2/2025

Express Delivery: Save 1 days

Compare

Add to wishlist

Get an offer