Comparison

Mesothelin / MSLN (298-600) Recombinant Protein

Item no. PRS-11-217-0.1mg
Manufacturer ProSci
Amount 0.1 mg
Category
Type Proteins Recombinant
Format Lyophilized
Applications WB, ELISA
Specific against other
Conjugate/Tag HIS
Purity >90% as determined by SDS-PAGE.
Sequence Asp 298 - Ser 600
Citations Chang K., et al., 1996, Proc. Natl. Acad. Sci. U.S.A. 93:136-140.
Yamaguchi N., et al., 1994, J. Biol. Chem. 269:805-808.
Rump A., et al., 2004, J. Biol. Chem. 279:9190-9198.
Ma J., et al., 2012, J. Biol. Chem. 287:33123-33131.
NCBI Msln
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias MSLN,Mesothelin,MPF
Shipping Condition Room temperature
Available
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight
36.0 kDa
Background
Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
By Type
Cancer
Buffer
PBS, pH7.4
Application Note
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.0 kDa. The protein migrates as 42-48 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Official Name
mesothelin
NCBI Organism
Mus musculus
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species
Mouse
By Species
Mouse

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.1 mg
Available: In stock
available

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