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EGF R Recombinant Protein

EGF R Recombinant Protein

Item no.	PRS-11-547-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Adenocarcinoma Western Blot ELISA Astrocytoma By Organ Bladder Cancer
Type	Proteins Recombinant
Format	Lyophilized
Applications	WB, ELISA
Specific against	other
Conjugate/Tag	Fc
Purity	>95% as determined by SDS-PAGE.
Sequence	Leu 25 - Ser 645
Citations	Herbst RS., 2004, Int. J. Radiat. Oncol. Biol. Phys. 59 (2 Suppl): 21–6. Giaccone, G., 2005, Ann. Onc. 16: 538-548.
NCBI	EGFR
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	EGFR,ERBB,ERBB1,HER1,PIG61,mENA
Available
Manufacturer - Applications	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 94.7 kDa. The protein migrates as 110-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Storage Conditions	Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Molecular Weight	94.7 kDa
Background	The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.
Buffer	PBS, pH7.4
NCBI Official Name	epidermal growth factor receptor
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 9/4/2025

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