Comparison

IL-6 Recombinant Protein (Animal Free)

Item no. PRS-40-744-2ug
Manufacturer ProSci
Amount 2 ug
Category
Type Proteins Recombinant
Format Lyophilized
Specific against other
Purity ≥ 98% by SDS-PAGE gel and HPLC analyses.
Sequence MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT
NCBI Il6
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias 26 kDa protein,IFN-β2,B cell differentiation factor (BCDF),BSF-2,HPGF,HSF,MGI-2
Shipping Condition Room temperature
Available
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
The recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Biological Activity
Determined by its ability to stimulate the proliferation of mouse 7TD1 cells. The expected ED50 is ≤ 0.02 ng/ml, corresponding to a specific activity of ≥ 5 x 107 units/mg.
Background
IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6Rα and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant Murine IL-6 is a 21.7 kDa protein containing 188 amino acid residues.
By Type
Immunology, Neuroscience, Stem Cell, Cancer, Obesity
NCBI Official Name
interleukin 6
NCBI Organism
Mus musculus
Disclaimer
This product is for research use only.
Manufacturer - Species
Human, Mouse, Monkey, Bacteria, Rat
By Species
Mouse

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 2 ug
Available: In stock
available

Delivery expected until 12/4/2025 

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