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DR6 Recombinant Protein

DR6 Recombinant Protein

Item no.	PRS-90-226-50ug
Manufacturer	ProSci
Amount	50 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Conjugate/Tag	Fc
Purity	>95% (SDS-PAGE).<br><br> Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Sequence	The Fc portion of human IgG1 is fused to the C-terminus of human DR6 (aa 42-351).
NCBI	TNFRSF21
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Tumor Necrosis Factor Receptor Superfamily Member 21,TNFRSF21,Death Receptor 6,CD358
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	Stable for at least 6 months after receipt when stored at -20˚ C.
Background	DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6.
By Type	Apoptosis
Protein Gi #	3549262
Concentration	1mg/ml after reconstitution.
Buffer	Contains PBS. Reconstitute with 50 μ l sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
Application Note	This recombinant proteins is for research use only.
NCBI Official Name	tumor necrosis factor receptor superfamily, member 21
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 1/1/2026

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