Comparison

IL-6 Recombinant Protein

Item no. PRS-90-290-10ug
Manufacturer ProSci
Amount 10 ug
Category
Type Proteins Recombinant
Format Lyophilized
Specific against other
Conjugate/Tag Fc
Purity >95% (SDS-PAGE).<br><br> Endotoxin level is less than 0.01EU/ μg protein (LAL test; Lonza).
Sequence The extracellular domain of mouse IL-6 (aa 25-211) is fused at the C-terminus to the Fc portion of human IgG2.
NCBI Il6
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Interleukin-6,B Cell Hybridoma Growth Factor,Interleukin HP-1
Shipping Condition Room temperature
Available
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Biological Activity
Promotes growth of hybridoma/plasma cells at concentration <0.1ng /ml.
Background
Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.
By Type
Chemokines & Cytokines, Immunology, Neuroscience
Protein Gi #
124348
Concentration
0.1 mg /ml after reconstitution
Buffer
Contains PBS. Reconstitute with 100 μ l sterile water.
Application Note
This recombinant proteins is for research use only.
NCBI Official Name
interleukin 6
NCBI Organism
Mus musculus
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species
Mouse
By Species
Mouse

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
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