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IL-6 Recombinant Protein

IL-6 Recombinant Protein

Item no.	PRS-90-482-50ug
Manufacturer	ProSci
Amount	50 ug
Category	Oncology Metabolism Diabetes Glucose Homeostasis By Cell Type Carcinoma Hematology Leukemia Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Conjugate/Tag	Fc
Purity	>98% (SDS-PAGE).<br><br> Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Sequence	The extracellular domain of human IL-6 (aa 30-212) is fused to the N-terminus of the Fc region of human IgG1.
NCBI	IL6
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Interleukin-6,B Cell Stimulatory Factor 2,BSF-2,CTL Differentiation Factor,CDF,Interferon beta2,IFN-beta2
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Background	Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.
By Type	Cancer, Chemokines & Cytokines, Immunology, Neuroscience, Obesity, Signal Transduction
Protein Gi #	10834984
Buffer	Lyophilized from 0.2um-filtered solution in PBS. Reconstitute in 50 μ l sterile water. Add 1X PBS to the desired protein concentration.
Application Note	This recombinant proteins is for research use only.
NCBI Official Name	interleukin 6
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 1/1/2026

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