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IL-1 alpha Recombinant Protein

IL-1 alpha Recombinant Protein

Item no.	PRS-91-031-0.05mg
Manufacturer	ProSci
Amount	0.05 mg
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Conjugate/Tag	Tag Free
Purity	Greater than 95% as determined by reducing SDS-PAGE.<br />Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Sequence	Ser115-Ser270
NCBI	Il1a
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Interleukin-1 Alpha,IL-1 Alpha,Il1a,IL-1F1,IL-1a
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	Lyophilized protein should be stored at -20˚ C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7˚ C for 2-7 days. Aliquots of reconstituted samples are stable at -20˚ C for 3 months.
Molecular Weight	18 kD
Biological Activity	ED50 is less than 0.01 ng/ml as determined by the dose-dependent stimulation of mouse D10S cells. Specific Activity of 1.0 x 10⁸ IU/mg.
Background	Mouse Interleukin-1 (IL-1) designates two proteins, IL-1 alpha and IL-1 beta , which are the products of distinct genes, but recognize the same cell surface receptors. IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa.
By Type	Apoptosis, Chemokines & Cytokines, Immunology, Innate Immunity
Buffer	Lyophilized from a 0.2 um filtered solution of 50mM TrisHCl, 200mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Application Note	This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name	interleukin 1 alpha
NCBI Organism	Mus musculus
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Mouse
By Species	Mouse

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.05 mg

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Delivery expected until 1/1/2026

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