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Proprotein Convertase 9 Recombinant Protein

Proprotein Convertase 9 Recombinant Protein

Item no.	PRS-91-783-0.05mg
Manufacturer	ProSci
Amount	0.05 mg
Category	Oncology Neuroscience Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Adhesion Molecules By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Obesity Lipoprotein Receptors & Associated Proteins Cardiovascular Research Ischemia & Reperfusion Injury By Organ Bladder Cancer
Type	Proteins Recombinant
Format	Liquid
Specific against	other
Conjugate/Tag	HIS
Purity	Greater than 95% as determined by reducing SDS-PAGE.<br />Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Dry ice	Yes
Sequence	Gln35-Gln692
NCBI	Pcsk9
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Proprotein Convertase Subtilisin/Kexin Type 9,Neural Apoptosis-Regulated Convertase 1,NARC-1,Proprotein Convertase 9,PC9,Subtilisin/Kexin-Like Protease PC9,Pcsk9,Narc1
Shipping Condition	Dry ice
Available
Manufacturer - Type	Recombinant Proteins
Manufacturer - Conjugate / Tag	C-6 His tag
Shipping Temperature	Dry Ice
Storage Conditions	Store at -20˚ C, stable for 6 months after receipt. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Molecular Weight	74.8 kD
Background	Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis.PCSK9 also plays a role in neural development.
Protein Gi #	291219911
Buffer	Supplied as a 0.2 um filtered solution of 50mM HEPES, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Application Note	This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name	proprotein convertase subtilisin/kexin type 9
NCBI Organism	Mus musculus
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Mouse
By Species	Mouse

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.05 mg

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Delivery expected until 2/5/2026

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