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IGF2 mRNA-Binding Protein 2 Recombinant Protein

IGF2 mRNA-Binding Protein 2 Recombinant Protein

Item no.	PRS-92-057-0.05mg
Manufacturer	ProSci
Amount	0.05 mg
Category	Oncology Neuroscience Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Protein Aggregation, Clearance & Misfolding By Cell Type Carcinoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Endocrine Regulation of Lipid Metabolism By Organ Hepatic Cancer
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Conjugate/Tag	HIS, T7 Epitope
Purity	Greater than 95% as determined by reducing SDS-PAGE.<br />Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Sequence	Met1-Thr220
NCBI	IGF2BP2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Insulin-Like Growth Factor 2 mRNA-Binding Protein 2,IGF2 mRNA-Binding Protein 2,IMP-2,Hepatocellular Carcinoma Autoantigen p62,IGF-II mRNA-Binding Protein 2,VICKZ Family Member 2,IGF2BP2,IMP2,VICKZ2
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Manufacturer - Conjugate / Tag	C-6 His, N-T7 tag
Shipping Temperature	Room Temp
Storage Conditions	Lyophilized protein should be stored at -20˚ C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7˚ C for 2-7 days. Aliquots of reconstituted samples are stable at -20˚ C for 3 months.
Molecular Weight	27.2 kD
Background	Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.
By Type	Homeostasis, Immunology, Obesity, Signal Transduction
Buffer	Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Application Note	This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name	insulin like growth factor 2 mRNA binding protein 2
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.05 mg

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Delivery expected until 1/1/2026

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