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NEDD8 Recombinant Protein

NEDD8 Recombinant Protein

Item no.	PRS-92-177-0.05mg
Manufacturer	ProSci
Amount	0.05 mg
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Autophagy
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Conjugate/Tag	HIS, SUMO
Purity	Greater than 95% as determined by reducing SDS-PAGE.<br />Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Sequence	Met1-Gly76
NCBI	NEDD8
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Neural precursor cell expressed developmentally down-regulated protein 8,NEDD8,Neddylin,Ubiquitin-like protein Nedd8
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Manufacturer - Conjugate / Tag	N-6 His, SUMO tag
Shipping Temperature	Room Temp
Storage Conditions	Lyophilized protein should be stored at -20˚ C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7˚ C for 2-7 days. Aliquots of reconstituted samples are stable at -20˚ C for 3 months.
Molecular Weight	20.9 kD
Background	Human NEDD8 shares 60% amino acid sequence identity to ubiquitin. The only known substrates of NEDD8 modification are the cullin subunits of SCF ubiquitin E3 ligases. The NEDDylation of cullins is critical for the recruitment of E2 to the ligase complex, thus facilitating ubiquitin conjugation. NEDD8 modification has therefore been implicated in cell cycle progression and cytoskeletal regulation.
By Type	Other
Buffer	Lyophilized from a 0.2 um filtered solution of 20mM PB，150mM NaCl，5% Trehalose, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Application Note	This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name	neural precursor cell expressed, developmentally down-regulated 8
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.05 mg

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Delivery expected until 1/1/2026

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