TSLP Receptor Recombinant Protein

C-6 His tag

Lyophilized protein should be stored at -20˚ C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚ C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚ C for 3 months.

The cytokine thymic stromal lymphopoietin receptor (TSLPR) is consisting of a common gamma receptor–like chain (TSLPR- gamma ) and a common interleukin 7 (IL-7) R alpha chain that belongs to the type 1 cytokine receptor family. Transfection of TSLPR cDNA result in only low affinity binding, while cotransfection of the IL-7R alpha chain cDNA shows high affinity binding. TSLP and TSLPR play a critical role in the initiation of allergic diseases in mice. The TSLP R cDNA encodes a transmembrane receptor containing 370 amino acids (aa) with two potential N-linked glycosylation sites and a cytoplasmic domain of 104 aa including a single tyrosine residue. TSLPR can mediate signaling of the signal transducer and activator of transcription 5 (Stat5) by TSLP. TSLP R is broadly expressed in the immune and hematopoietic cells, particularly in hematopoietic progenitors and myeloid cells.

929654682

This recombinant protein can be used for biological assays. For research use only.

Mus musculus

Mouse

CRL2, CRLF2, CRLM-2, PCOR1, CRL2 cytokine receptor, CRL2 precusor, CRLF2Y, Cytokine receptor-like 2, cytokine receptor-like factor 2, ILXR, IL-XR, P2RY8/CRLF2 fusion, Thymic stromal lymphopoietin protein receptor, Thymic stromal-derived lymphopoietin receptor, TSLP receptor, TSLPR, TSP R