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SLAMF 4 Recombinant Protein

SLAMF 4 Recombinant Protein

Item no.	PRS-96-001-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Oncology Neuroscience Metabolism Glucose Homeostasis Aging & Neurological Disorders Peptides & Proteins Recombinant Proteins Western Blot By Organ Lung Cancer Breast Cancer Testicular & Prostate Cancer
Type	Proteins Recombinant
Format	Lyophilized
Applications	WB
Specific against	other
Conjugate/Tag	HIS
Purity	>95% as determined by SDS-PAGE.
Sequence	Cys 22 - Arg 221
Citations	Nakajima H., et al., 1999, Eur. J. Immunol. 29:1676-1683. Kubin M.Z., et al., 1999, Eur. J. Immunol. 29:3466-3477. Boles K.S., et al., 1999, Tissue Antigens 54:27-34.
NCBI	CD244
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD244,2B4,SLAMF4,NKR2B4,NAIL,h2B4
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight	23.1 kDa
Biological Activity	Measured by its binding ability in a functional ELISA. Immobilized rh CD244 / 2B4 at 2μ g/ml (100μ l/well) can bind human CD48. The EC50 of human CD48 is 0. 39μ g/ml.
Background	Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
By Type	Immunology, Stem Cell
Buffer	PBS, pH7.4
Application Note	This recombinant protein can be used for WB. For research use only.
NCBI Official Name	CD244 molecule, natural killer cell receptor 2B4
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 2/5/2026

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