« Back
Home /
LIF Recombinant Protein (HEK293 Expressed)

LIF Recombinant Protein (HEK293 Expressed)

Item no.	PRS-96-519-0.02mg
Manufacturer	ProSci
Amount	0.02 mg
Category	Oncology Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Recombinant Proteins Obesity Western Blot By Organ Heart & Blood Cancer
Type	Proteins Recombinant
Format	Lyophilized
Applications	WB
Specific against	other
Conjugate/Tag	Tag Free
Purity	>95% as determined by SDS-PAGE.
Sequence	Ser 23 - Phe 202
Citations	Wenwei Hu, Zhaohui Feng, Angelika K. Teresky1, Arnold J. Levine (November 29, 2007). Kawahara Y, Manabe T, Matsumoto M, Kajiume T, Matsumoto M, Yuge L (2009). PLoS ONE 4 (7): e6343. Patterson PH (1994). Proc. Natl. Acad. Sci. U.S.A. 91 (17).
NCBI	LIF
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LIF,CDF,DIA,HILDA,MLPLI
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight	19.9 kDa
Biological Activity	Determined by its ability to stimulate the proliferation of human TF-1 cells. The ED50 <0. 1 ng/mL, corresponding to a specific activity of >1X107 Unit/mg.
Background	Leukemia inhibitory factor, or LIF, an interleukin 6 class cytokine, is a protein in cells that affects cell growth and development.Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. Therefore LIF is used in mouse embryonic stem cell culture. It is necessary to maintain the stem cells in an undifferentiated state, however genetic manipulation of embryonic stem cells allows for LIF independent growth, notably overexpression of the gene Nanog. LIF is not required for culture of human embryonic stem cells.
By Type	Stem Cell
Buffer	PBS, pH7.4
Application Note	This recombinant protein can be used for WB. For research use only.
NCBI Official Name	leukemia inhibitory factor
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 0.02 mg

available

Delivery expected until 2/5/2026

Express Delivery: Save 15 days

Compare

Add to wishlist

Get an offer