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LIFR Recombinant Protein

LIFR Recombinant Protein

Item no.	PRS-96-522-0.2mg
Manufacturer	ProSci
Amount	0.2 mg
Category	Oncology Metabolism Diabetes Glucose Homeostasis By Cell Type Carcinoma Hematology Lymphoma Myeloma Melanoma Peptides & Proteins Recombinant Proteins Western Blot By Organ Heart & Blood Cancer
Type	Proteins Recombinant
Format	Lyophilized
Applications	WB
Specific against	other
Conjugate/Tag	Fc
Purity	>95% as determined by SDS-PAGE.
Sequence	Gln 45 - Ser 833
Citations	Timmermann, Andreas, et al. 2002, Eur. J. Biochem. (Germany) 269 (11): 2716–26. Gearing, D.P. et al.,1991, EMBO J. 10 (10): 2839-2848. Gearing, D.P. et al.,1992, New Biol. 4 (1): 61-65. Mosley, B. et al.,1996, J. Biol. Chem. 271 (51): 32635-32643.
NCBI	LIFR
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LIFR,CD118,FLJ98106,FLJ99923,SJS2,STWS,SWS
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Manufacturer - Conjugate / Tag	C-Fc Tag
Shipping Temperature	Room Temp
Storage Conditions	Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight	115.5 kDa
Biological Activity	Measured by its binding ability in a functional ELISA. Immobilized Human LIF, Tag Free at 0.2ug/mL (100 uL/well) can bind Human LIF R, Fc Tag with a linear range of 7.8-31.25 ng/mL.
Background	Leukemia inhibitory factor receptor is also known as LIFR; CD118; FLJ98106; FLJ99923; LIF-R; SJS2; STWS; SWS, is the receptor for leukemia inhibitory factor (LIF). The leukemia inhibitory factor is a polyfunctional cytokine that affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIF action appears to be mediated through a high-affinity receptor complex composed of a low-affinity LIF binding chain (LIF receptor) and a high-affinity converter subunit, gp130. Both LIFR and gp130 are members of a family of cytokine receptors that includes components of the receptors for the majority of hematopoietic cytokines and for cytokines that affect other systems, including the ciliary neurotrophic factor, growth hormone and prolactin Defects in LIFR are the cause of Stueve-Wiedemann syndrome (SWS), a severe autosomal recessive condition and belongs to the group of the bent-bone dysplasias.
Buffer	Tris with Glycine, Arginine and NaCl, pH7.5
Application Note	This recombinant protein can be used for WB. For research use only.
NCBI Official Name	leukemia inhibitory factor receptor alpha
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.2 mg

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Delivery expected until 2/5/2026

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