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Serpin E2 Recombinant Protein

Serpin E2 Recombinant Protein

Item no.	PRS-96-683-0.025mg
Manufacturer	ProSci
Amount	0.025 mg
Category	Oncology Food Safety Proteins Peptides & Proteins Recombinant Proteins Western Blot By Organ Breast Cancer
Type	Proteins Recombinant
Format	Lyophilized
Applications	WB
Specific against	other
Conjugate/Tag	HIS
Purity	>92% as determined by SDS-PAGE.
Sequence	Ser 20 - Pro 397
Citations	Gloor S.M., et al., 1986, Cell 47:687-693. Scott R.W., et al., 1985, J. Biol. Chem. 260:7029-7034.
NCBI	SERPINE2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	SERPINE2, Glia-derived nexin, GDN, Peptidase inhibitor 7, PI-7, Protease nexin 1, PN-1, Serpin E2, SerpinE2, PI7
Available
Manufacturer - Applications	This recombinant protein can be used for WB. For research use only.
Storage Conditions	Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Molecular Weight	42.7 kDa
Biological Activity	Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca - RPKPVE - Nval - WRK(Dnp) - NH2.
Background	SERPINE2 is also known as Glia-derived nexin (GDN), Peptidase inhibitor 7 (PI7), Protease nexin 1(PN1). SERPINE2 is a secreted glycoprotein which belongs to the serpin family. SerpinE1 is the primary physiological inhibitor of the two plasminogen activators urokinase (uPA) and tissue plasminogen activator (tPA). PAI-1 / GDN is also implicated in adipose tissue development. It suggests that PAI-1 inhibitors serve in the control of atherothrombosis. Defects in Serpin E1 / PN1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency) which is characterized by abnormal bleeding due to SerpinE1 defect in the plasma.
Buffer	20 mM NaAc, 100 mM NaCl, PH6.5
NCBI Official Name	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.025 mg

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Delivery expected until 9/4/2025

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