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VEGF R3 Recombinant Protein

VEGF R3 Recombinant Protein

Item no.	PRS-96-961-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Oncology Neuroscience Metabolism Diabetes Molecular Targets for Neuroscience Aging & Neurological Disorders By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Cell Status Adenocarcinoma Cell Metabolism Western Blot ELISA Oxidative Stress By Organ Bladder Cancer
Type	Proteins Recombinant
Format	Lyophilized
Applications	WB, ELISA
Specific against	other
Conjugate/Tag	Fc
Purity	>95% as determined by SDS-PAGE.<br><br>Endotoxin level is less than 1.0 EU per ug by the LAL method.
Sequence	Tyr 25 - Ile 776
Citations	Stuttfeld E., et al., 2009, IUBMB Life, 61 (9): 915-922. Zygmunt T., et al., 2011, Dev Cell, 21 (2): 301-314. Herzog, B., et al., 2011, Molecular Biology of the Cell, 22 (15): 2766-2776.
NCBI	VEGF R3
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Flt-4,FLT4,LMPH1A,PCLFLT41,VEGFR3,VEGFR-3,FLT-4,FLT-41,FLT41,PCL
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight	111.2 kDa
Biological Activity	Measured by its binding ability in a functional ELISA. Immobilized Human VEGF-C, His Tag at 5 ug/mL (100 uL/well) can bind Human VEGF R3, Fc Tag with a linear range of 0.6-10 ng/mL.
Background	Vascular endothelial growth factor receptor 3 (VEGF R3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). VEGF R3 mediates lymphangiogenesis in response to VEGF-C and VEGF-D. VEGF R3 is widely expressed in the early embryo but becomes restricted to lymphatic endothelia at later stages of development. It is likely that VEGF R3 may be important for lymph angiogenesis.
By Type	Immunology
Buffer	Tris with Glycine, Arginine and NaCl, pH7.5
Application Note	This recombinant protein can be used for E, WB. For research use only.
NCBI Official Name	vascular endothelial growth factor receptor 3 isoform 2 precursor
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 12/4/2025

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