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Vaccinia Virus B18R Recombinant Protein

Vaccinia Virus B18R Recombinant Protein

Item no.	PRS-97-072-0.05mg
Manufacturer	ProSci
Amount	0.05 mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Adenocarcinoma Western Blot Astrocytoma By Organ Bladder Cancer
Type	Proteins Recombinant
Format	Lyophilized
Applications	WB, ELISA
Specific against	other
Conjugate/Tag	HIS
Purity	>95% as determined by SDS-PAGE.<br><br>Endotoxin level is less than 1.0 EU per ug by the LAL method.
Sequence	His 20 - Glu 351
Citations	Alcami A., et al., 2000, J. Virol. 74:11230-11239. Waibler Z., et al., 2009, J. Virol. 83:1563-1571.
NCBI	B18R
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	B18R
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight	40.3 kDa
Background	B18R is a type I interferon (IFN)-binding protein and it is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus, which contains two Ig-like C2-type domains and one Ig-like V-type domain. B18R exists in a soluble and a membrane-bound form. As a type I IFN receptor, B18R counteracts the antiviral effects of host IFN-alpha/beta. Also, B18R acts as a soluble IFN-alpha receptor and thus inhibits the interaction between host IFN-alpha and its receptor.
By Type	Infectious Disease
Buffer	PBS, pH7.4
Application Note	This recombinant protein can be used for WB. For research use only.
NCBI Official Name	Soluble interferon alpha/beta receptor B18
NCBI Organism	Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Vaccinia Virus
By Species	Other

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.05 mg

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Delivery expected until 2/5/2026

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