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Amphiregulin

Amphiregulin

Item no.	RLT-M10-019
Manufacturer	ReliaTech
Amount	50ug
Category	Oncology By Cell Type Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Synonyms	AR, AREG, Colorectum cell-derived growth factor (CRDGF)
Detection range	Determined by its ability to stimulate the proliferation of mouse Balb/c 3T3 cells. The expected ED50 for this effect is 5-10 ng/ml.
Description	Amphiregulin is an EGF-related growth factor that signals through the EGF/TGF-alpha receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin's extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant Murine Amphiregulin is an 11.3 kDa glycoprotein consisting of 98 amino acid residues.
Formulation	lyophilized
Length (aa)	98
Protein Sequence	SVRVEQVIKP KKNKTEGEKS TEKPKRKKKG GKNGKGRRNK KKKNPCTAKF QNFCIHGECR YIENLEVVTC NCHQDYFGER CGEKSMKTHS EDDKDLSK
NCBI GeneID	11839
Accession Number Protein	NP_033834.1?
Accession Numberm RNA	NM_009704.4
Uniprot	P31955

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 8/21/2025

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