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Calotatug ginistinag

Calotatug ginistinag

Item no.	HY-164919
Manufacturer	MedChem Express
CASRN	2847102-44-5
Amount	1 ea
Category	Reagents & Chemicals Ligands & Crosslinkers Crosslinkers
Type	Crosslinkers
Specific against	other
Citations	[1]Duvall J R, et al. XMT-2056, a HER2-targeted Immunosynthen STING-agonist antibody-drug conjugate, binds a novel epitope of HER2 and shows increased anti-tumor activity in combination with trastuzumab and pertuzumab[J]. Cancer Res, 2022, 82(12_Supplement): 3503-3503.
Smiles	[Calotatug ginistinag]
ECLASS 10.1	32170205
ECLASS 11.0	32170205
UNSPSC	41105316
Alias	XMT-2056
Shipping Condition	Room temperature
Available
Manufacturer - Type	ADC Related
Manufacturer - Applications	Cancer-programmed cell death
Shipping Temperature	Room temperature
Molecular Weight	N/A
Product Description	Calotatug ginistinag (XMT-2056) is an antibody-drug conjugate targeting HER2, with an effective payload connected via a linker (LP, HY-148067) to a STING agonist (STING agonist-20, HY-148068), and has potential immune activation and anticancer activity[1].
Manufacturer - Research Area	Cancer; Inflammation/Immunology
Manufacturer - Pathway	Antibody-drug Conjugate/ADC Related; Immunology/Inflammation; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Isoform	ErbB2/HER2
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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