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Importazole

Importazole

Item no.	LSHB-OP-2000001810-5mg
Manufacturer	Life Science Hub
CASRN	662163-81-7
Amount	5 mg
Category	Reagents & Chemicals APIs general
Type	Chemicals
Specific against	other
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Additional information - Category	Biochemical Compounds
Storage Conditions	RT
Storage Buffer	White solid
Background	Specifically inhibits importin-β-mediated nuclear import without disrupting transportin-mediated nuclear import or CRM1-mediated nuclear export1. When added to cells during mitosis it impairs the release of an importin- cargo probe and causes defects in spindle assembly. Inhibition of importin-β function is most likely mediated by blocking its interaction with RanGTP. It is an important new tool to probe the function of the importin-/RanGTP pathway2-4. Cell permeable
Description	Chemical Name: N-(1-Phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amine Molecular weight: 318.43 Formula: C20H22N4 Solubility: DMSO (10 mg/ml) Physical Properties: Off-white solid Purity: 97% by TLC, NMR (Conforms)

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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