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Cilastatin Na

Cilastatin Na

Item no.	LSHB-OP-2000002018-50mg
Manufacturer	Life Science Hub
CASRN	81129-83-1
Amount	50 mg
Category	Reagents & Chemicals APIs general
Type	Chemicals
Specific against	other
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Additional information - Category	Biochemical Compounds
Storage Conditions	-20°C
Storage Buffer	Yellow solid
Background	Dehydropeptidase-1 inhibitor. Inhibits the proteolytic conversion of leukotriene D4 to E4.1 Inhibits the mammalian β-lactamase renal dipeptidase (dehydropeptidase-1, DPEP1) and thus is used as an antibacterial adjunct to extend the half-life of β-lactam antibiotics.2 Cilastatin also inhibits bacterial metallo-β-lactamase and thereby may block resistance to the carbapenem family of antibiotics in certain bacteria.3 Suppresses invasion and metastasis of DPEP1-expressing tumor cells.4
Description	Chemical Name: (2Z)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2, 2-dimethylcyclopropyl]-carbonyl]amino]-2-heptenoic acid, sodium salt Molecular weight: 380.43 Formula: C16H25N2O5S Na Solubility: DMSO (3 mg/ml) Water (35 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms)

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