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Norquetiapine · 2HCl

Norquetiapine · 2HCl

Item no.	LSHB-OP-2000002107-50mg
Manufacturer	Life Science Hub
CASRN	111974-74-4
Amount	50 mg
Category	Reagents & Chemicals APIs general
Type	Chemicals
Specific against	other
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Additional information - Category	Biochemical Compounds
Storage Conditions	RT
Storage Buffer	White solid
Background	Pharmacologically active metabolite of quetiapine.1 Exhibits distinct pharmacological activity from quetiapine and plays an important role in its antidepressant activity.2 Activates ERK1/2 and induces release of BDNF in C6 glioma cells which may contribute to the antidepressant properties of quetiapine.3 Inhibits the norepinephrine transporter which may contribute to the antipsychotic activity of quetiapine.4
Description	Chemical Name: 11-(1-Piperazinyl)-dibenzo[b, f][1, 4]thiazepine dihydrochloride Molecular weight: 368.32 Formula: C17H17N3S 2HCl Solubility: DMSO, Methanol Water Physical Properties: Off-white solid Purity: 98% by TLC, NMR (Conforms)

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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